Our mission is to ensure the generation of accurate and precise findings.
Contact Us Ta-134/A, Gulshan Badda Link 61 383 766 284 noreply@envato.comAt S4 Research, we drive global clinical research in India—helping bring life-changing treatments to those who need them most.
Founded in 2015 and headquartered in Ahmedabad, India, S4 Research is India’s leading Site Management Organization (SMO) — trusted by global biopharma companies and CROs for our hands-on execution, quality data, and unmatched recruitment capabilities.
With unparalleled access to leading hospitals/clinics/research centers, strong relationships with top investigators, and a patient-first approach, we help sponsors accelerate enrollment, navigate regulations with confidence, and ensure flawless operational execution for clinical trials.
Whether it's a rare disease trial or a high-volume study, our model scales with precision—accelerating activation and enrollment, and delivering quality data with an excellent patient experience.
Ali brings over 23 years of experience in global clinical research, with a solid foundation in both strategic and operational roles across global, regional, and country levels.
He began his career as a CRA with ICON, and later joined Kendle (now Syneos Health), where he progressed through roles of increasing responsibility—from Lead CRA to Project Manager, Project Director, and ultimately Regional Director of Clinical Operations for Asia-Pacific. In this leadership role, he successfully managed a team of 125 clinical research professionals across the region.
Ali’s entrepreneurial vision led him to establish and lead the India-based operations for Orphan Reach, a UK-based global rare disease CRO supporting its worldwide business. As a key leadership team member, he played an instrumental role in positioning Orphan Reach as one of the most respected rare disease-focused CROs globally. The organization was ultimately acquired by a major global CRO through a successful strategic transaction.
In 2015, Ali founded S4 Research, which has since grown into one of India’s leading site support organizations. Under his leadership, S4 has delivered multiple clinical trials across a wide range of therapeutic areas, with a focus on hard-to-recruit populations—including multiple rare disease studies.
Ali brings deep expertise in strategic feasibility, innovative patient recruitment methodologies, patient-centric solutions, and building strong relationships with investigators, sites, and patient groups. Known for building and scaling high-performing teams, he remains dedicated to advancing clinical research excellence in India and helping patients gain early access to treatment.
Ali is a clinical pharmacist and an alumnus of the prestigious National Institute of Pharmaceutical Education and Research (NIPER), where he graduated as a gold medalist.
Dr. Akshay Shah (BHMS, MSc Clinical Research, PGDPM, CCRA) is a seasoned clinical research professional with 20 years of experience in the global clinical trials industry. His expertise spans clinical operations, site management, regulatory submissions, quality oversight, and strategic site development across a wide range of therapeutic areas.
He began his career in 2005, gaining hands-on experience through progressive roles at organizations such as Kendle (now Syneos Health), Encorium, Biosensors International, and Reliance Life Sciences. Dr. Shah has overseen more than 1,500 monitoring and oversight visits across studies in ophthalmology, cardiology, oncology, dermatology, neurology, gastroenterology, vaccines, infectious diseases, and rare conditions such as CIDP, SLE, and DMD. He is known for his meticulous approach, deep regulatory knowledge, and commitment to delivering high-quality, patient-centered research.
In 2013, he founded Quality First Research and Healthcare Solutions, a specialized Site Management Organization (SMO) focused on building high-performing investigator sites across India. Under his leadership, the organization earned a strong reputation for operational excellence and reliable trial execution. In 2017, it was strategically integrated into S4 Research, with Dr. Shah continuing in a leadership role in the company post-acquisition.
Following the acquisition, Dr. Shah took on the role of Director at S4 Research, where he has played a key role in strengthening its nationwide SMO network, building scalable operational frameworks, and enhancing sponsor-site engagement. His leadership has been central to S4’s growth as one of India’s most trusted site support partners for global clinical trials.
He holds an MSc in Clinical Research from Cranfield University (UK), in collaboration with ICRI, a Postgraduate Diploma in Pharmaceutical Management, and has been an ACRP-certified Clinical Research Associate since 2010. He is also an alternative medicine graduate and previously served as a medical officer in a neonatal ICU and a urology hospital.
Reach out to start a conversation and see how we can collaborate or support your clinical studies.