Our mission is to ensure the generation of accurate and precise findings.
Contact Us Ta-134/A, Gulshan Badda Link 61 383 766 284 noreply@envato.com
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Our mission is to ensure the generation of accurate and precise findings.
Contact Us Ta-134/A, Gulshan Badda Link 61 383 766 284 noreply@envato.com
With an extensive network of sites and strong connections to key opinion leaders (KOLs) and specialty investigators, S4 offers valuable feasibility intelligence for your studies. We provide early-stage protocol feedback, supporting biopharmaceutical companies and CROs in optimizing clinical trial planning.
S4 accelerates data-driven feasibility assessments for your clinical trials. Topline feedback is delivered within 24 hours, while comprehensive multi-site feasibility reports are provided within two weeks
Relationships with engaged investigators and experienced sites
On the ground team of feasibility champions for fast turnaround and quality delivery
Broad site network across India with combination of Government and Private Sites
Protocol Analysis & Early Scientific Input for better study designs
Alignment with Sponsor expectations thereby delivering expected results
Our commitment to quality and performance begins with strategic and efficient start-up planning. With our extensive experience, we recognize the common challenges that can delay study initiation.
Our streamlined processes and dedicated start-up team ensure timely approvals, rapid contract execution, and readiness for site initiation—enabling faster first-patient-in (FPI) timelines.
Our efficient, centrally managed start-up processes enable our network sites to achieve activation timelines at least two months faster than non-network sites. This head start accelerates patient enrollment, enhances overall study efficiency, and contributes to meaningful time and cost savings for our clients.
We offer our clients a single point of contact for all sites, ensuring centralized coordination of key start-up activities such as:
Collection of site-specific information for regulatory and ethics submissions
Compilation of essential, critical, and regulatory green light documents
Finalization of Informed Consent Forms, incorporating site-specific changes
Coordination of initial and ongoing submissions to ethics and research committees (where applicable)
Contract negotiation and execution
Identification and support of site-specific infrastructure and study requirements
Completion of study-specific training and facilitation of access to necessary study systems
Delays in patient recruitment remain one of the most critical bottlenecks in clinical development. Nearly 4 out of 5 trials fail to recruit on time, and almost 50% require extensions—leading to spiraling costs, disrupted timelines, missed market opportunities and delayed access to treatment.
At S4, we take a strategic, data-driven, and collaborative approach to accelerate patient recruitment
In close collaboration with both our sites and sponsors, we apply a comprehensive toolkit and proven methodology, including:
Recruitment Projection Calculators to estimate realistic, measurable enrollment timelines
Site-Specific Recruitment Plans tailored to each site's capacity and population access
Patient Outreach Strategies, including community engagement and digital campaigns
Defined Patient Flow & Logistics Mapping to ensure smooth onboarding and retention
Ongoing Performance Monitoring to proactively address recruitment barriers
S4 achieves 2.5 times higher enrollment rates compared to industry averages.
80% of our studies meet or exceed enrollment targets before the Last Patient In (LPI) deadline.
Our sites experience 20% fewer screen failures than others, improving patient eligibility and trial efficiency.
Suboptimal patient retention significantly increases trial costs and prolongs timeline. On average, up to 30% of clinical trial delays are caused by poor patient retention. A retention rate drop from 90% to 70% can extend trial duration by 3–6 months, resulting in $1.8M to $48M in added costs for a single large Phase III trial.
At S4, we recognize that retaining patients once enrolled is just as critical as recruiting them. Strong retention ensures complete, compliant, and high-quality data sets, ultimately contributing to trial success and regulatory confidence.
We have implemented structured, patient-centric retention processes designed to keep participants engaged and supported throughout the study. Our approach includes:
Tailored retention programs customized to the study population and protocol
Proactive identification and management of potential drop-out risks
Analysis and resolution of barriers preventing patients from returning for follow-up visits
Deployment of effective retention tools and strategies at the site and patient level
Dedicated personnel to maintain regular contact with patients and caregivers
Timely and transparent travel reimbursement to minimize logistical burdens
S4 sites achieve a 95% participant retention rate, ensuring consistent study engagement.
100% on-time patient reimbursements, minimizing financial barriers.
Nearly all patients (98%) felt valued and cared for while participating in our studies.
At S4, we ensure all our clinical trial sites operate seamlessly within established Standard Operating Procedures (SOPs) and benefit from our dedicated onsite staff. This consistent framework guarantees high-quality execution, compliance, and operational efficiency across every site.
Our Commitment to Site Excellence:
Uniform SOP
Adherence
Every site follows our rigorously defined SOPs, ensuring standardized processes and consistent quality.
Dedicated
Onsite Staff
Our experienced personnel are embedded at all sites, providing hands-on support and expert oversight.
Collaborative
KPI & KQI
We work with clients to set clear KPIs and KQIs, ensuring aligned objectives and measurable success.
Reduced Deviations
& Screen Failures
We ensure near-zero protocol deviations and reduced screen failure through site management.
Inspection-Ready
Investigator Site Files
Our sites maintain ISFs that are audit-ready, minimizing risks during regulatory inspections.
Equipment &
Calibration Support
We assist sites with equipment maintenance and calibration to ensure data accuracy and compliance.
Timely Data Entry &
Query Resolution
Data entry in 3 days, queries in 24 hrs-ensuring data integrity and study continuity.
Continuous Source
Data Review
Our staff conduct ongoing SDR to ensure completeness and accuracy of clinical data.